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Microbiology and Biotechnology Letters

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Food, Environment, and Other Topics in Biotechnology

Microbiol. Biotechnol. Lett. 2012; 40(4): 364-370

https://doi.org/10.4014/kjmb.1207.07007

Received: July 16, 2012; Accepted: September 19, 2012

도화(Prunus persica Flos) 분획물의 미백 및 주름개선 효과

Whitening and Anti-wrinkle Effects of fractions from Prunus persica Flos

Jin-Young Lee 1 and Bong-Jeun An 2*

1Department of Herbal Cosmetic Science, Hoseo University, 2Department of Cosmeceutical Science, Daegu Haany University

Abstract

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In this study, the compounds of Prunus persica Flos were extracted with 70.0% acetone and were purified using a sephadex-LH-20 column chromatography. As a result, eight fractions were isolated. For whitening effects, the tyrosinase inhibitory activity was determined to be 92.2% in Fr.-8 isolated from P. persica Flos at 1.000 ppm. The melanoma cell-originated tyrosinase inhibitory effect of Fr.-8 from P. persica Flos was approximately 63.4% at 100 ppm. The inhibitory activity on melanin synthesis by Fr.-8 isolated from P. persica Flos was about 71.7% at 100 ppm concentration. For anti-wrinkling effects, the elastase inhibition activities by Fr.-5, 7 isolated from P. persica Flos were around 71.4 and 74.5% respectively at 1,000 ppm. The collagenase inhibition activity and collagen synthesis by Fr.-8 isolated from P. persica Flos was about 80.0% at 100 ppm. All these findings suggested that the fractions of P. persica Flos have great potential as cosmeceutical ingredients with whitening and anti-wrinkling effects.

Keywords: Prunus persica Flos, whitening, anti-wrinkle, melanin, collagen

References

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