Characterization of an Antimicrobial Substance-producing Pseudomonas sp. BCNU 2001

Uk-Hee  Yang; Hye-Jung  Choi; Cheol-Soo  Ahn; Yong-Kee  Jeong; Dong-Wan  Kim; Woo-Hong  Joo

Microbiol. Biotechnol. Lett. 2010; 38(3): 255-262

항생물질을 생산하는 Pseudomonas sp. BCNU 2001 균주의 특성

Characterization of an Antimicrobial Substance-producing Pseudomonas sp. BCNU 2001

Uk-Hee Yang , Hye-Jung Choi , Cheol-Soo Ahn , Yong-Kee Jeong , Dong-Wan Kim and Woo-Hong Joo

Interdisciplinary Program in Biotechnology & Department of Biology, Changwon National University, ¹Interdisciplinary Program in Biotechnology & Department of Biology, Changwon National University, ²Cho-A Pharm. Co. LTD., ³Department of Biotechnology, Dong-A University, ⁴Department of Microbiology, Changwon National University, ⁵Interdisciplinary Program in Biotechnology & Department of Biology, Changwon National University

Abstract

Go to

Abstract

Strain BCNU 2001 was isolated from soil samples collected from Tea-baek Mountain area. The biochemical characteristics and 16S ribosomal RNA gene sequences of the isolate revealed that the strain belonged to the Pseudomonas aeruginosa. The supernatants had an antimicrobial effect on various kind of bacteria and fungi. Especially BCNU 2001 was able to greatly inhibit the growth of Micrococcus luteus, Proteus mirabilis, Proteus vulgaris, and Aspergillus niger, and its inhibition zone was measured as 18.5 mm against Micrococcus luteus, 19.0mm against Proteus mirabilis, 17.0mm against Proteus vulgaris, and 13.5 mm against Aspergillus niger, respectively. Hexane and dichloromethane extracts of BCNU 2001 exhibited significant activity against bacteria, and dichloromethane and ethylacetate extracts showed significant activity against fungi. Pseudomonas strain BCNU 2001 was also determined to have antimicrobial peptide against various microorganisms including Gram positive bacteria, Gram negative bacteria and fungi. The obtained results may provide preliminary support for the usefulness of Pseudomonas strain BCNU 2001.

Keywords: Tea-baek Mountain, antibacterial activity, antifungal activity, broad-spectrum antibiotics

Article Tools

Share this article on :

Most Searched Keywords ?
What is Most Searched Keywords?

It is most registrated keyword in articles at this journal during for 2 years.

eISSN 2234-7305
pISSN 1598-642X

Download to citation(s)

Yang UH, Choi HJ, Ahn CS, Jeong YK, Kim DW, Joo WH. Characterization of an Antimicrobial Substance-producing Pseudomonas sp. BCNU 2001. Microbiol. Biotechnol. Lett 2010;38:255-262.

Download to citation(s)
Export type	* Please select a format and type blew.
Format	EndNote Reference Manager RIS Format Plain Text

항생물질을 생산하는 Pseudomonas sp. BCNU 2001 균주의 특성