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Microbiology and Biotechnology Letters

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Microbiol. Biotechnol. Lett. 2010; 38(1): 1-6

모유 올리고당과 분유첨가 Prebiotic 올리고당의 관한 고찰

Human Milk Oligosaccharides and Prebiotic Oligosaccharides in Infant Formula

Chang-Ho Chung

Department of Food Service Management, Sejong University

Abstract

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Human milk is frequently the only food source for a newborn during the initial stage of life after birth. Milk provides not only the nutrients necessary for the infant's growth, but also ingredients that may enable the infant to thrive. Human milk oligosaccharides (HMO) are considered to be these beneficial ingredients for the health of infant. It has been reported that around 5 to 10 g unbound oligosaccharides and around 20 to over 130 different HMO are present in 1L of human milk. The suggested health mechanisms of HMO's roles in host defense are 1) blocking bacterial adhesions, 2) binding to a toxin receptor on the extracellular domain, and 3) postbiotic effect resulting from the increase of probiotics such as Bifidobacteria and Lactobacilli. Among the prebiotic oligosaccharides, mixtures of long chain fuetooligosaccharides (10%) and galactooligosaccharides (90%) in infant formula are demonstrated to increase the number of Bifidobacteria and Lactobacilli to the levels seen in human milk fed infants.

Keywords: Human milk, breast milk, oligosaccharides, human milk oligosaccharides, prebiotics

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