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Microbiology and Biotechnology Letters

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Molecular and Cellular Microbiology (MCM)  |  Host-Microbe Interaction and Pathogenesis

Microbiol. Biotechnol. Lett. 2021; 49(2): 249-254

https://doi.org/10.48022/mbl.2010.10014

Received: October 22, 2020; Revised: January 14, 2021; Accepted: January 29, 2021

Human Mastadenovirus Infections and Meteorological Factors in Cheonan, Korea

Eun Ju Oh1†, Joowon Park2†, and Jae Kyung Kim3*

1Department of Medical Laser, Dankook University Graduate School of Medicine, Cheonan 31116, Republic of Korea 2Department of Laboratory Medicine, Dankook University College of Medicine, Cheonan 31116, Republic of Korea 3Department of Biomedical Laboratory Science, Dankook University College of Health Sciences, Cheonan 31116, Republic of Korea

Correspondence to :
Jae Kyung Kim,      nerowolf2@dankook.ac.kr

These authors contributed equally to this work.

The study of the impact of weather on viral respiratory infections enables the assignment of causality to disease outbreaks caused by climatic factors. A better understanding of the seasonal distribution of viruses may facilitate the development of potential treatment approaches and effective preventive strategies for respiratory viral infections. We analyzed the incidence of human mastadenovirus infection using real-time reverse transcription polymerase chain reaction in 9,010 test samples obtained from Cheonan, South Korea, and simultaneously collected the weather data from January 1, 2012, to December 31, 2018. We used the data collected on the infection frequency to detect seasonal patterns of human mastadenovirus prevalence, which were directly compared with local weather data obtained over the same period. Descriptive statistical analysis, frequency analysis, t-test, and binomial logistic regression analysis were performed to examine the relationship between weather, particulate matter, and human mastadenovirus infections. Patients under 10 years of age showed the highest mastadenovirus infection rates (89.78%) at an average monthly temperature of 18.2℃. Moreover, we observed a negative correlation between human mastadenovirus infection and temperature, wind chill, and air pressure. The obtained results indicate that climatic factors affect the rate of human mastadenovirus infection. Therefore, it may be possible to predict the instance when preventive strategies would yield the most effective results.

Keywords: Climate, mastadenovirus, respiratory viruses, infection, particulate matter, weather

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