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Microbiology and Biotechnology Letters

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Molecular and Cellular Microbiology / Biomedical Sciences  |  Clinical Microbiology and Biomedical Sciences

Microbiol. Biotechnol. Lett. 2018; 46(4): 430-433

https://doi.org/10.4014/mbl.1806.06010

Received: June 22, 2018; Accepted: July 17, 2018

Prevalence of Hepatitis B Virus Infection in Kaifeng,China: A 5-year Observation

Jinli Zhang 1, Chunyan Ma 1, Hang Li 1, Michael Steele 2 and Adi Idris 1, 3*

1Department of Clinical Laboratory, Kaifeng Central Hospital, Kaifeng, Henan, China, 2School of Allied Health, Faculty of Health Sciences, Australian Catholic University, Queensland, Australia, 3Menzies Health Institute Queensland, School of Medical Science, Griffith University, Gold Coast, Queensland, Australia

Hepatitis B is a major health problem in China. However, little is known about the prevalence of hepatitis B virus (HBV) in Kaifeng, the major urban capital of Henan province, China. We found that HBV prevalence increased with age and that chronic HBV was predominant in adult males in Kaifeng. The HBV prevalence remained unchanged over a 5-year period for all age groups. Alarmingly, 25% of the population remained unvaccinated and potentially susceptible to future HBV infection. HBV immunization and health education initiatives should be carried out in this population to further reduce the overall prevalence of HBV.

Keywords: Hepatitis B virus, Kaifeng, China, HBsAg

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