![View PDF](/asset/img/sub/view-pdf.png)
Molecular and Cellular Microbiology / Biomedical Sciences | Clinical Microbiology and Biomedical Sciences
Microbiol. Biotechnol. Lett. 2018; 46(4): 430-433
https://doi.org/10.4014/mbl.1806.06010
Received: June 22, 2018; Accepted: July 17, 2018
Prevalence of Hepatitis B Virus Infection in Kaifeng,China: A 5-year Observation
Jinli Zhang 1, Chunyan Ma 1, Hang Li 1, Michael Steele 2 and Adi Idris 1, 3*
1Department of Clinical Laboratory, Kaifeng Central Hospital, Kaifeng, Henan, China, 2School of Allied Health, Faculty of Health Sciences, Australian Catholic University, Queensland, Australia, 3Menzies Health Institute Queensland, School of Medical Science, Griffith University, Gold Coast, Queensland, Australia
Hepatitis B is a major health problem in China. However, little is known about the prevalence of hepatitis
B virus (HBV) in Kaifeng, the major urban capital of Henan province, China. We found that HBV prevalence
increased with age and that chronic HBV was predominant in adult males in Kaifeng. The HBV prevalence
remained unchanged over a 5-year period for all age groups. Alarmingly, 25% of the population
remained unvaccinated and potentially susceptible to future HBV infection. HBV immunization and health
education initiatives should be carried out in this population to further reduce the overall prevalence of
HBV.
Keywords: Hepatitis B virus, Kaifeng, China, HBsAg
Li W, Gao Z, Yang C, Li J, Li L, Lv R, et al. 2013. The estimation of prevalence, incidence, and residual risk of transfusion-transmitted human hepatitis B infection from blood donated at the Anhui blood center, China, from 2009 to 2011. PLoS One 8:e73472.
Chen YS, Li L, Cui FQ, Xing WG, Wang L, Jia ZY, et al. 2011. [A seroepidemiological study on hepatitis C in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 32: 888-891.
Yong Hao G, Da Xing F, Jin X, Xiu Hong F, Pu Mei D, Jun L, et al. 2017. The prevalence of hepatitis B infection in central China: An adult population-based serological survey of a large sample size. J. Med. Virol. 89: 450-457.
Li L, Han T, Zang L, Niu L, Cheng W, Lin H, et al. 2017. The current incidence, prevalence, and residual risk of hepatitis B viral infections among voluntary blood donors in China. BMC Infect Dis. 17:754.
Chen P, Xie Q, Chen T, Wu J, Wu J, Ruan B, et al. 2017. Hepatitis B virus infection in hilly/mountainous regions of southeastern China: a locality-dependent epidemiology. BMC Infect Dis. 17:809.
Luo Z, Xie Y, Deng M, Zhou X, Ruan B. 2011. Prevalence of hepatitis B in the southeast of China: a population-based study with a large sample size. Eur. J .Gastroenterol. Hepatol. 23: 695-700.
Makvandi M. 2016. Update on occult hepatitis B virus infection. World J. Gastroenterol. 22: 8720-8734.
Zu J, Zhuang G, Liang P, Cui F, Wang F, Zheng H, et al. 2017. Estimating age-related incidence of HBsAg seroclearance in chronic hepatitis B virus infections of China by using a dynamic compartmental model. Sci Rep. 7: 2912.
Goyal A, Murray JM. 2017. Roadmap to control HBV and HDV epidemics in China. J. Theor. Biol. 423: 41-52.